USAGE PATTERNS OF AROMATHERAPY ESSENTIAL OIL AMONG CHINESE CONSUMERS.




Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead

Abstract Covalent drugs can achieve high potency with long dosing intervals.However, concerns remain about side-effects associated with off-target reactivity.Combining macrocyclic peptides with covalent warheads provides a solution to minimise off-target reactivity: the peptide enables highly specific target binding, positioning Baby Mobiles a weak

read more